One of the key questions in biology is how the metabolism of a cell responds to changes in the environment.In budding yeast, starvation causes a drop in intracellular pH, but the functional role of this pH change is not well understood.Here, we show that the enzyme glutamine synthetase (Gln1) forms filaments at low pH and that filament formation So
Each species of intestinal bacteria requires a nutritional source to maintain its population in the intestine.Dietary factors are considered to be major nutrients; however, evidence directly explaining the in situ utilization of dietary factors is limited.Microscale bacterial distribution would provide clues to understand bacterial lifestyle Suppli
Medial patellar instability, though infrequently recognized, can be a disabling Sun Hat complication of a lateral retinacular release.Patients with persistent anterior knee pain and instability after lateral release should be evaluated closely.If evidence of increased medial patellar translation is identified on physical examination, a trial of rev